Early Detection Can Save Life and Prevent the Suffering and Cost of Treating Disease
- Many cancers and other complex disease are detected late.
- Late detection results in increased morbidity and death
- Examples; liver, lung and gastric cancer
- Current biomarkers lack sensitivity and specificity to detect disease early.
- Available biomarkers and diagnostic methods are invasive; can’t be used for follow-up of healthy populations
- Not applicable for follow up of large “healthy” populations that are at risk
Our Services
EPILIVER
Patent pending
Early detection of liver cancer
- Detects conversion of patients with chronic hepatitis or healthy controls to early stage liver cancer HCC
- Targets were clinically validated in studies in Yuan hospital in Beijing published in Clinical Epigenetics 2018. PCT world patent protection in national stage (US, Europe, Canada, Indonesia, India, Japan)
- Next generation sequencing assay fully optimized clinically tested
HKG EPITHERAPEUTICS STRATEGY
- DNA methylation marks are an exquisite “ID” of a cell representing its past experiences and predicting its future.
- The exquisite profile of DNA methylation marks in white blood cells is mapped at the earliest stage of disease. Computational methods are used to reveal a combination of marks (polygenic) that can predict the earliest appearance of disease
- Next generation sequencing methods are optimized to develop a high throughput robust assay for polygenic markers of disease.
